Mthfr gene ablation enhances susceptibility to arsenic prenatal toxicity
نویسندگان
چکیده
منابع مشابه
Mthfr gene ablation enhances susceptibility to arsenic prenatal toxicity.
BACKGROUND In utero exposure to arsenic is known to adversely affect reproductive outcomes. Evidence of arsenic teratogenicity varies widely and depends on individual genotypic differences in sensitivity to As. In this study, we investigated the potential interaction between 5,10-methylenetetrahydrofolate reductase (Mthfr) genotype and arsenic embryotoxicity using the Mthfr knockout mouse model...
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ژورنال
عنوان ژورنال: Toxicology and Applied Pharmacology
سال: 2014
ISSN: 0041-008X
DOI: 10.1016/j.taap.2013.12.014